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This area of the problem regulates reward responses in getting food and sex, plus nurturing infants and children. One of the most important neurotransmitters linked to reward responses, both after they malfunction and once they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates "the quantity of dopamine released in in response to a stimulus"(Bostwick & Bucci, 2008). Using two separate drugs to shed weight can be very effective you will find combinations before the FDA now awaiting approval. When dealing with weight loss and the those who go through it you should err to the side of caution and permit the FDA do its job and demand some investigation be done so that the public recognizes the side effects and risks of the medications before we bring them. Keep in mind that drug companies are in business to earn money and that they would say anything to keep people on their own medications. Researchers found out that participants using this drug for the year, lost weight within one month and have kept the load off during the entire 56 weeks from the study. Contrave is often a combination of the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which can be made up of many active ingredient, which may make them more efficient and safer. Combo-pilling will be the newest fad or even better the newest ahead under scrutiny and so it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that employing a combination of pills has become popular could be the fact that as of right now there aren't any long term prescription diet pills that have been licensed by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be approved by the FDA. Seizures certainly are a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug could also raise blood pressure and pulse rate, and mustn't be used in those with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure and heart rate and must not used in patients with uncontrolled high hypertension, as well as by you are not heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients using a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients towards the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking. To maintain your most current articles from Wendi, the Indiana Addiction Recovery Examiner, click on the subscribe link towards the top of the page to obtain email notification when new content is published. Please leave a comment for any article.